Detalhe da pesquisa
1.
Highly active CAR T cells that bind to a juxtamembrane region of mesothelin and are not blocked by shed mesothelin.
Proc Natl Acad Sci U S A
; 119(19): e2202439119, 2022 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35512094
2.
Dromedary camel nanobodies broadly neutralize SARS-CoV-2 variants.
Proc Natl Acad Sci U S A
; 119(18): e2201433119, 2022 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35476528
3.
Identification of nurse shark VNAR single-domain antibodies targeting the spike S2 subunit of SARS-CoV-2.
FASEB J
; 37(6): e22973, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37191949
4.
Soluble programmed death ligand-1-induced immunosuppressive effects on chimeric antigen receptor-natural killer cells targeting Glypican-3 in hepatocellular carcinoma.
Immunology
; 169(2): 204-218, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640111
5.
Role of glypican-1 in regulating multiple cellular signaling pathways.
Am J Physiol Cell Physiol
; 321(5): C846-C858, 2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34550795
6.
Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice.
Gastroenterology
; 158(8): 2250-2265.e20, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32060001
7.
Engineered Anti-GPC3 Immunotoxin, HN3-ABD-T20, Produces Regression in Mouse Liver Cancer Xenografts Through Prolonged Serum Retention.
Hepatology
; 71(5): 1696-1711, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31520528
8.
Recombinant immunotoxins with albumin-binding domains have long half-lives and high antitumor activity.
Proc Natl Acad Sci U S A
; 115(15): E3501-E3508, 2018 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29581296
9.
32A9, a novel human antibody for designing an immunotoxin and CAR-T cells against glypican-3 in hepatocellular carcinoma.
J Transl Med
; 18(1): 295, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32746924
10.
A Frizzled-Like Cysteine-Rich Domain in Glypican-3 Mediates Wnt Binding and Regulates Hepatocellular Carcinoma Tumor Growth in Mice.
Hepatology
; 70(4): 1231-1245, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30963603
11.
Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.
Hepatology
; 70(2): 563-576, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30353932
12.
Therapeutically targeting glypican-2 via single-domain antibody-based chimeric antigen receptors and immunotoxins in neuroblastoma.
Proc Natl Acad Sci U S A
; 114(32): E6623-E6631, 2017 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28739923
13.
Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma.
Proc Natl Acad Sci U S A
; 110(12): E1083-91, 2013 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23471984
14.
Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican-3 for liver cancer therapy.
Hepatology
; 60(2): 576-87, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24492943
15.
Glypican-3 targeted human heavy chain antibody as a drug carrier for hepatocellular carcinoma therapy.
Mol Pharm
; 12(6): 2151-7, 2015 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25955255
16.
Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability.
Nat Commun
; 15(1): 285, 2024 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177144
17.
Role of sorafenib in the treatment of advanced hepatocellular carcinoma: An update.
Hepatol Res
; 43(2): 147-54, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23145926
18.
Humanization of the Shark VNAR Single Domain Antibody Using CDR Grafting.
Curr Protoc
; 3(1): e630, 2023 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-36594750
19.
Human VH-based chimeric antigen receptor T cells targeting glypican 3 eliminate tumors in preclinical models of HCC.
Hepatol Commun
; 7(2): e0022, 2023 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36691969
20.
The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer.
Nat Commun
; 14(1): 1986, 2023 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37031249